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From: Dr. Steve
Date: 15 Dec 2005
Time: 10:04:09 -0800
Remote Name: 12.10.202.94
Oxycodone is a semisynthetic narcotic analgesic derived by chemical modification from codeine. You stated that "oxycodone did not cross-react with opiate screens." I guess my next question to you is what particular screen was being used? Did you do the screen or did the lab do the screen? There are some "opiate screens" that test positive for all opiates. See the abstract Forensic Drug Testing for Opiates IV and this review article on oxycodone.
As you can see there are several assays was found to be highly selective for free morphine, whereas other assays demonstrated broad cross-reactivity with other opiates (like oxycodone) In NIDA labs, when they are doing testing for DOT purposes, where oxycodone is not one of the opiates that they test, they are only screening for morphine, codeine and heroin. Obviously you did the right thing by having the specimen confirmed by GC/MS testing.
You also ask what is the time ranges for detecting oxycodone in urine are (at 300 ng cutoff)? In the previous thread I stated that, "Morphine and codeine can be detected approximately for up to 4 days." This is also true for oxycodone as well. A positive test for oxycodone can be explained by a legitamate prescription and use of oxycodone 24-36 hours before the test.
And as for the great site, we only have Dr. Swotinsky to blame.....errrrr.....thank for this!