Alcohol metabolism

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jdkjoy

Alcohol metabolism

Post by jdkjoy » Mon Jun 14, 2010 3:35 pm

Is the rate of alcohol elimination from the body affected by birth control pills or smoking?



DrSteve

Re: Alcohol metabolism

Post by DrSteve » Mon Jun 14, 2010 5:21 pm

I suspect anything might, however can you give us a background for the reason you are asking this question. In what context? Why? Etc. Thanks.

jdkjoy

Re: Alcohol metabolism

Post by jdkjoy » Mon Jun 14, 2010 5:52 pm

Trying to determine if a female who smokes and on birth control pills would affect her rate of elimination regarding alcohol.

DrSteve

Re: Alcohol metabolism

Post by DrSteve » Mon Jun 14, 2010 6:08 pm

jdkjoy wrote:Trying to determine if a female who smokes and on birth control pills would affect her rate of elimination regarding alcohol.

Why? Did she test + for alcohol? We need more information.

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Re: Alcohol metabolism

Post by Robert Swotinsky MD » Mon Jun 14, 2010 8:46 pm

While there is some evidence of testosterone as a hormonal influence on alcohol metabolism, there is no evidence that female sex hormones (e.g., BCPs) influence alcohol metabolism. [Source: Garriott J, ed. Medical-Legal Aspects of Alcohol, 4th Ed. Tuscon, AZ: Lawyers & Judges Publishing Company, Inc., 2003, page 71.] I'm not aware of smoking effecting ethanol metabolism. Someone who smokes a lot and has COPD may not be able to provide a deep-lung sample on a breath test, but that's a different kind of concern.

The factors known to slow alcohol metabolism are malnourishment, low-protein dites, advanced cirrhosis, and administration of the drug fomepizole. THe factors known to speed up alcohol metabolism are history of drinking, IV administration of fructose, induction of CYP2E1 enzymes by drrugs or ethanol, hypermetabolic state (e.g., burn trauma victims), and genetic predisposition as a fast metabolizer.

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